Association between musk antibody concentrations and the myasthenia gravis composite score in 3 patients: A marker of relapse?
James Douglas TriplettTodd A HardyD Sean RimintonShannon Y K ChuStephen W ReddelPublished in: Muscle & nerve (2019)
A close relationship existed between the MuSK-Ab concentrations and the MGC score. Furthermore, a rise in Ab concentration preceded a more serious clinical relapse in all patients Conclusions: These findings suggest that MuSK-Ab concentrations may be a useful biomarker for the long-term monitoring of MuSK myasthenia gravis, particularly while in clinical remission. This may allow preemptive escalation of therapy to prevent clinical relapse, and conversely permitting greater weaning of unnecessary immunosuppression. Muscle Nerve, 2019.
Keyphrases
- myasthenia gravis
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- clinical trial
- skeletal muscle
- intensive care unit
- rheumatoid arthritis
- disease activity
- mechanical ventilation
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- peripheral nerve