Telomere shortening and accelerated aging in COPD: findings from the BODE cohort.
A Elizabeth Córdoba-LanúsSara Cazorla-RiveroAdriana Espinoza-JiménezJuan P de-TorresMaría J PajaresArmando Aguirre-JaimeBartolomé CelliCiro CasanovaPublished in: Respiratory research (2017)
Compared with smokers, patients with COPD have accelerated telomere shortening and this rate of attrition depends on baseline telomere length. Furthermore, the telomere length and its rate of shortening did not relate to clinical and lung function parameters changes over 3 years of follow-up.