Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult.

Mohammad Sarif MohiuddinTatsuhito HimenoRieko InoueEmiri Miura-YuraYuichiro YamadaHiromi Nakai-ShimodaSaeko AsanoMakoto KatoMikio MotegiMasaki KondoYusuke SeinoShin TsunekawaYoshiro KatoAtsushi SuzukiKeiko NaruseKoichi KatoJiro NakamuraHideki Kamiya

Published in: Journal of diabetes research (2019)

Our findings indicate that GLP-1RAs have neuroprotective potential which is achieved by their direct actions on DRG neurons. Beneficial effects of GLP-1RAs on DPN could be related to these direct actions on DRG neurons.

Keyphrases

spinal cord
neuropathic pain
wild type
spinal cord injury
human health
blood brain barrier