Diagnostic performance of S100B as a rule-out test for intracranial pathology in head-injured patients presenting to the emergency department who meet NICE Head Injury Guideline criteria for CT-head scan.
Alice RoganAnnabelle SikEmily DickinsonVimal PatelBrad PecklerDavid McQuadePeter D Larsennull nullPublished in: Emergency medicine journal : EMJ (2022)
Within 6 hours of injury, S100B performed well as a diagnostic test to exclude significant intracranial pathology in low-risk patients presenting with head injury. In theory, if used in addition to NICE HIGs, CT-head rates could reduce by one-quarter with a potential miss rate of <1%.
Keyphrases
- optic nerve
- emergency department
- computed tomography
- end stage renal disease
- dual energy
- chronic kidney disease
- ejection fraction
- newly diagnosed
- magnetic resonance imaging
- image quality
- peritoneal dialysis
- magnetic resonance
- contrast enhanced
- risk assessment
- prognostic factors
- positron emission tomography
- patient reported