Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.

James LileyMichael NewnhamMarta BledaKatherine BunclarkWilliam AugerJoan Albert BarberaHarm BogaardMarion DelcroixTimothy M FernandesLuke HowardDavid JenkinsIrene LangEckhard MayerChris RhodesMichael SimpsonLaura SouthgateRichard TrembathJohn WhartonMartin R WilkinsStefan GräfNicholas MorrellJoanna Pepke ZabaMark R Toshner

Published in: American journal of respiratory and critical care medicine (2024)

Chronic thromboembolic pulmonary hypertension is a partially heritable polygenic disease, with related though distinct genetic associations to pulmonary embolism and to deep vein thrombosis.

Keyphrases

pulmonary embolism
pulmonary hypertension
inferior vena cava
pulmonary artery
pulmonary arterial hypertension
atrial fibrillation
genome wide
single cell
gene expression
dna methylation