GTPase-activating protein ARAP1 regulates circular dorsal ruffles as a nutrient uptake mechanism in the Hep3B hepatocellular carcinoma cell line.

Xiaowei Sun Yanan LiYuxin HeLongjiao ChengJinzi WeiLinxuan DuZhongyang ShenSei Yoshida

Published in: bioRxiv : the preprint server for biology (2024)

ARAP1 regulates circular dorsal ruffles (CDRs) in the Hep3B HCC cell line and deletion of this protein attenuates malignant potential, thereby indicating the involvement of CDRs in cancer development.

Keyphrases

spinal cord
neuropathic pain
protein protein
papillary thyroid
signaling pathway
amino acid
binding protein
squamous cell
spinal cord injury
small molecule
young adults
childhood cancer