Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics.

Brian MadajewskiFeng ChenBarney YooMelik Z TurkerKai MaLi ZhangRupa JuthaniVirginia Aragon-SanabriaMithat Gönen Charles M RudinUlrich WiesnerMichelle S BradburyCameron Brennan

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)

Results underscore the clinical potential of DFO-Gef-C' dots to effectively manage disease and minimize off-target effects at a fraction of the native drug dose.

Keyphrases

iron oxide
small molecule
emergency department
drug induced
cancer therapy
human health
single molecule
drug delivery
climate change
high resolution
tandem mass spectrometry