SHCBP1 promotes tumor cell proliferation, migration, and invasion, and is associated with poor prostate cancer prognosis.

Ning XuYu-Peng WuHu-Bin YinShao-Hao ChenXiao-Dong LiXue-Yi XueXin Gou

Published in: Journal of cancer research and clinical oncology (2020)

These findings suggest that SHCBP1 overexpression contributes to PCa progression and that targeting SHCBP1 might be therapeutically beneficial to patients with PCa.

Keyphrases

cell proliferation
prostate cancer
radical prostatectomy
cell cycle
cancer therapy
transcription factor
pi k akt
signaling pathway