Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis-associated infertility.

Louise E GloverDavid CrosbyUma ThiruchelvamCathal HarmonCáit Ni ChorcoraMary B WingfieldCliona O'Farrelly

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)

Our study revealed that uterine NK progenitor cell populations are markedly different in patients with endometriosis who proceed to successful or failed embryo implantation and may define a novel predictor of implantation success. Our findings also highlight the fundamental differences inherent in NK cell repertoires between blood and uterine compartments.

Keyphrases

nk cells
single cell
stem cells
metabolic syndrome
pregnant women
insulin resistance