Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis-associated infertility.
Louise E GloverDavid CrosbyUma ThiruchelvamCathal HarmonCáit Ni ChorcoraMary B WingfieldCliona O'FarrellyPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2018)
Our study revealed that uterine NK progenitor cell populations are markedly different in patients with endometriosis who proceed to successful or failed embryo implantation and may define a novel predictor of implantation success. Our findings also highlight the fundamental differences inherent in NK cell repertoires between blood and uterine compartments.