Molecular Profiling of Malignant Pleural Effusion in Metastatic Non-Small-Cell Lung Carcinoma. The Effect of Preanalytical Factors.

Jamal CarterJames Adam MillerDavid Feller-KopmanDavid EttingerDavid SidranskyZahra Maleki

Published in: Annals of the American Thoracic Society (2018)

Molecular profiling of MPE is a viable alternative to testing solid tissue in NSCLC. This study shows successful detection of genetic aberrations in 59% of samples with minimal risk of false negative.

Keyphrases

single cell
small cell lung cancer
copy number
cell therapy
single molecule
genome wide
advanced non small cell lung cancer
stem cells
label free
brain metastases
real time pcr