Cerebral Amyloid Angiopathy-Related Inflammation and Biopsy-Positive Primary Angiitis of the CNS: A Comparative Study.
Lou GrangeonGregoire BoulouisJean CapronFouzi BalaDimitri RenardNicolas RaposoOzlem Ozkul-WermesterAude Triquenot-BaganXavier AyrignacDavid WallonEmmanuel GerardinPhilippe KerschenDenis SablotMaïté FormaglioFernando PicoGuillaume TurcMarc VernyLisa HumbertjeanMarie GaudronStéphane VannierNelly DequatreBenoît GuillonClothilde IsabelCaroline ArquizanOlivier DetanteSophie GodardBarbara CasollaMichael LevrautCédric GollionMathieu Gerfaud-ValentinLaurent KremerLaure DaelmanNicolas LambertSylvain LanthierAlexandre Y PoppeAlexis RégentDavid Weisenburger-LilePierre VerdureGérald QuesneyMathieu VautierAnne WacongneEric ThouvenotJérémie ParienteSarah CoulettePierre M LabaugeNadège OlivierThibaut AllouHelene ZephirAntoine NéelSaskia BreschBenjamin TerrierOlivier MartinaudRomain SchneckenburgerThomas PapoChloé Comarmond-OrtoliEric JouventMarie SubrévilleLouis Poncet-MegemontMuhammad Amer KhatibFrançois LunCarole HenryEloi MagninQuentin ThomasMathilde GraberYassine BoukricheGeneviève Blanchet-FourcadeDiana RatiuChristian PagnouxEmmanuel TouzéHubert de BoyssonSonia AlamowitchAhmad NehmePublished in: Neurology (2024)
Clinicoradiologic features differed between patients with CAA-RI and those with BP-PACNS. Specific markers for CAA-RI were hemorrhagic signs of subarachnoid involvement, past intracerebral hemorrhage, ≥21 visible centrum semiovale perivascular spaces, and the probable CAA-RI criteria. A biopsy remains necessary for diagnosis in some cases of CAA-RI. The rate of relapse in the first 2 years after disease remission was lower in CAA-RI than in BP-PACNS.