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Sex hormone-dependent and -independent regulation of serum BAFF and TNF in cohorts of transgender and cisgender men and women.

Christos TsatsanisAngel ElenkovIrene LeijonhufvudKaterina VaporidiÅsa TivestenAleksander Giwercman
Published in: Endocrine connections (2023)
Sex hormones and sex chromosomes have different impacts on cytokines involved in the sex-dependent inflammatory response. The concentration of BAFF and LPS-stimulated TNF secretion depended on sex hormone levels, whereas basal TNF was regulated by both sex hormone-dependent and -independent factors.
Keyphrases
  • inflammatory response
  • rheumatoid arthritis
  • lps induced