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Targeted systemic therapies for psoriatic arthritis: a systematic review and comparative synthesis of short-term articular, dermatological, enthesitis and dactylitis outcomes.

Iain B McInnesLaura Marie SawyerKristen MarkusCorinne LeReunCelia Sabry-GrantPhilip S Helliwell
Published in: RMD open (2022)
Despite similar efficacy for ACR response, IL-17A and IL-17RA inhibitors and guselkumab offered preferential efficacy to anti-TNFs in skin manifestations, and for enthesitis and dactylitis, thereby supporting drug selection based on predominant clinical phenotype.
Keyphrases
  • juvenile idiopathic arthritis
  • rheumatoid arthritis
  • type diabetes
  • cancer therapy
  • soft tissue
  • emergency department
  • skeletal muscle
  • drug delivery
  • drug induced
  • wound healing
  • adverse drug
  • weight loss