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CAISC: A software to integrate copy number variations and single nucleotide mutations for genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing.

Jeerthi KannanLiza MathewsZhijie WuNeal S YoungShouguo Gao
Published in: BMC bioinformatics (2022)
CAISC is a powerful tool for integration of CNV and SNV data from scRNA-seq to identify clonal clusters with better accuracy than obtained from a single type of data. CAISC allows users to interactively examine clonal assignments.
Keyphrases
  • single cell
  • copy number
  • rna seq
  • mitochondrial dna
  • genome wide
  • high throughput
  • electronic health record
  • big data
  • loop mediated isothermal amplification
  • machine learning
  • deep learning