Collagen-Based Photoactive Agent for Tissue Bonding.

Justina PupkaiteManuel AhumadaSarah MclaughlinMaha TemkitSura AlazizRichard SeymourMarc RuelIrene KochevarMay GriffithErik J SuuronenEmilio I Alarcon

Published in: ACS applied materials & interfaces (2017)

Using a combination of methacrylated collagen and the photosensitizer rose Bengal, a new light-activated biomimetic material for tissue sutureless bonding was developed. This formulation was cross-linked using green light. In vivo tests in mice demonstrate the suitability of the material for sutureless wound closure.

Keyphrases

wound healing
tissue engineering
photodynamic therapy
drug delivery
high fat diet induced
adipose tissue
skeletal muscle