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Micromanaging checkpoint proteins.
Andrea Ciliberto
Silke Hauf
Published in:
eLife (2017)
The kinase Mps1, long known to be the 'boss' in mitotic checkpoint signaling, phosphorylates multiple proteins in the checkpoint signaling cascade.
Keyphrases
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cell cycle
dna damage
cell proliferation
oxidative stress
tyrosine kinase
protein kinase