Longitudinal cardiac magnetic resonance imaging following clinical response to rilonacept and prior to recurrence upon treatment suspension: a RHAPSODY subgroup analysis.
Paul C CremerAntonio Luca BrucatoAntonella InsalacoDavid LinSushil Allen LuisDeborah H KwonChristine L JellisJoAnn ClairAllison CurtisSheldon WangAllan L KleinMassimo ImazioJohn F PaoliniPublished in: European heart journal. Cardiovascular Imaging (2024)
Continued clinical improvement during prolonged rilonacept treatment corresponded with improvement on CMR, including reduced pericardial thickness, resolution of pericardial edema, and resolution of LGE. However, none/trace LGE at 18MDM while on treatment did not predict absence of pericarditis recurrence upon subsequent rilonacept suspension in this size-limited subgroup.