Login / Signup

Bioactive Compounds from Abelmoschus manihot L. Alleviate the Progression of Multiple Myeloma in Mouse Model and Improve Bone Marrow Microenvironment.

Jianhao HouJinjun QianZhenlin LiAixiu GongSixia ZhongLi QiaoShihui QianYanxin ZhangRenjie DouRui LiYe YangChunyan Gu
Published in: OncoTargets and therapy (2020)
These results of the present study indicated that the bio-active ingredients of HKC exerted protective effects on MM mouse survival through promoting osteoblastogenesis and suppressing osteoclastogenesis, thus improving the bone marrow microenvironment to inhibit MM cell proliferation.
Keyphrases
  • bone marrow
  • mouse model
  • cell proliferation
  • multiple myeloma
  • mesenchymal stem cells
  • stem cells
  • signaling pathway
  • cell cycle
  • free survival