Severe hypersensitivity reactions to biological drugs in children with rheumatic diseases.
Ozge SoyerSelcan DemirYelda BilginerEzgi Deniz BatuHafize Emine SonmezZehra Serap ArıcıÜmit Murat ŞahinerBulent Enis SekerelSeza OzenPublished in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2019)
The frequency of severe immediate HSR due to BD was shown to be 3.9% in children with rheumatic diseases. Children with active rheumatic disease and who have exposure to multiple BD should be monitored for BD HSR, particularly during intravenous BD infusions.