NTCP modeling and dose-volume correlations for acute xerostomia and dry eye after whole brain radiation.
Panayiotis MavroidisKevin A PearlsteinDominic H MoonVictoria XuTrevor J RoyceAshley A WeinerColette J ShenLawrence B MarksBhishamjit S CheraShiva K DasKyle WangPublished in: Radiation oncology (London, England) (2021)
Xerostomia was most associated with parotid V10Gy-V20Gy, and dry eye with lacrimal V10Gy-V15Gy. NTCP models were successfully created for both toxicities and may help clinicians refine dosimetric goals and assess levels of risk in patients receiving palliative WBRT.
Keyphrases
- palliative care
- liver failure
- radiation therapy
- resting state
- white matter
- respiratory failure
- small cell lung cancer
- drug induced
- radiation induced
- brain injury
- multiple sclerosis
- hepatitis b virus
- intensive care unit
- cerebral ischemia
- acute respiratory distress syndrome
- blood brain barrier
- extracorporeal membrane oxygenation