COVID-MATCH65-A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2.

Jason A TrublanoSara VogrinOlivia C SmibertNada MarhoonAdrian A AlexanderKyra Y L ChuaFiona L JamesNicholas R L JonesSam E GriggCecilia L H XuNasreen MoiniSam R StanleyMichael T BirrellMorgan T RoseClaire L GordonJason C KwongNatasha E Holmes

Published in: PloS one (2020)

From the largest prospective outpatient cohort of suspected COVID-19 we define the clinical factors predictive of a positive SARS-CoV-2 test. The subsequent clinical decision rule, COVID-MATCH65, has a high sensitivity and NPV for SARS-CoV-2 and can be employed in the pandemic, adjusted for disease prevalence, to aid COVID-19 risk-assessment and vital testing resource allocation.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
risk assessment
risk factors
heavy metals
human health
decision making