Plasma levels of complement components C5 and C9 are associated with thrombin generation.

Rocío Vacik DíazGaëlle MunschMaria Jesus IglesiasAlejandro Pallares RoblesManal Ibrahim-KostaJamie NourseEssak KhanElisabetta CastoldiNoémie SautAnne BolandMarine GermainJean-François DeleuzeJacob OdebergPierre-Emmanuel MorangeSven DanckwardtDavid-Alexandre TregouëtLouisa Goumidi

Published in: Journal of thrombosis and haemostasis : JTH (2024)

This study identified complement proteins C5 and C9 as potential determinants of thrombin generation. Further studies are warranted to establish causality and elucidate the underlying mechanisms.

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