Impact of prothrombotic genotypes on the association between family history of myocardial infarction and venous thromboembolism.

Birgit SmåbrekkeLudvig B RindeLine H EvensenVania M MorelliKristian HveemMaiken E GabrielsenInger NjølstadEllisiv B MathiesenFrits R RosendaalSigrid K BraekkanJohn-Bjarne Hansen

Published in: Journal of thrombosis and haemostasis : JTH (2019)

Our findings suggest that the risk of VTE by FHMI is not explained by rs8176719 (ABO), rs6025 (F5), rs1799963 (F2), rs2066865 (FGG), and rs2036914 (F11). The combination of FHMI with prothrombotic genotypes had an additive effect on VTE risk.

Keyphrases

venous thromboembolism
direct oral anticoagulants
heart failure
left ventricular
atrial fibrillation