Augmenting serotonin reuptake inhibitors in obsessive-compulsive disorder: What moderates improvement?

Michael G WheatonDavid RosenfieldEdna B FoaH Blair Simpson

Published in: Journal of consulting and clinical psychology (2015)

SRI augmentation with EX/RP was more effective than risperidone across all of the demographic and clinical variables tested. EX/RP's superiority over risperidone increased with baseline OCD severity and with younger age. These data indicate that EX/RP should be the recommended SRI augmentation strategy, even for severe OCD. What determines the degree of EX/RP response in individual patients deserves further study.

Keyphrases

obsessive compulsive disorder
deep brain stimulation
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
soft tissue
peritoneal dialysis
early onset
electronic health record
deep learning