Effects of clotrimazole troches on tacrolimus dosing in heart transplant recipients.

Melissa R LaubStacy A CrowHeather A PersonettRoss DierkhisingBarry BoilsonRaymund Razonable

Published in: Transplant infectious disease : an official journal of the Transplantation Society (2018)

In conclusion, clotrimazole troches exert a meaningful interaction with tacrolimus that requires close monitoring and dose adjustment. The data from this single-center study provide novel information that could guide providers on the degree of tacrolimus dose adjustment needed when discontinuing clotrimazole prophylaxis after heart transplantation.

Keyphrases

heart failure
atrial fibrillation
big data
machine learning
deep learning