Transformation of Meloxicam Containing Nanosuspension into Surfactant-Free Solid Compositions to Increase the Product Stability and Drug Bioavailability for Rapid Analgesia.
Csaba BartosRita AmbrusGábor KatonaTamás SoványRóbert GáspárÁrpád MárkiEszter DuczaAnita IvanovFerenc TömösiTamás JanákyPiroska Szabó-RévészPublished in: Drug design, development and therapy (2019)
The solidification of the nanosuspension not only increased the stability of the Mel nanoparticles but also allowed the preparation of surfactant-free compositions with excellent bioavailability which may be an important consideration for certain groups of patients to achieve rapid analgesia.
Keyphrases
- end stage renal disease
- pain management
- newly diagnosed
- chronic kidney disease
- ejection fraction
- ultrasound guided
- prognostic factors
- peritoneal dialysis
- loop mediated isothermal amplification
- postoperative pain
- risk assessment
- molecularly imprinted
- heavy metals
- drug induced
- sensitive detection
- electronic health record