Continuous flow left ventricular assist devices do not worsen endothelial function in subjects with chronic heart failure: a pilot study.
Francesca CorteseMarco Matteo CicconeMichele GesualdoMassimo IacovielloMaria FrigerioManlio CiprianiCristina GiannattasioAlessandro MalobertiPaola GiordanoPublished in: ESC heart failure (2021)
Continuous flow related to LVAD seems to not worsen endothelial function. Endothelial function was not affected by cardiovascular risk factors (hypertension, hypercholesterolaemia, diabetes, obesity, and tobacco habit), by the functional status expressed by New York Heart Association class, by the left ventricular systolic function and by the presence or absence of ischaemic heart disease in all the populations analysed. CRP was the only factor able to influence percentage of FMD change in patient with LVAD, reinforcing the hypothesis that inflammation is the main determinant of endothelial function.
Keyphrases
- left ventricular
- cardiovascular risk factors
- metabolic syndrome
- heart failure
- cardiovascular disease
- type diabetes
- blood pressure
- hypertrophic cardiomyopathy
- cardiac resynchronization therapy
- acute myocardial infarction
- left atrial
- aortic stenosis
- insulin resistance
- mitral valve
- oxidative stress
- left ventricular assist device
- case report
- weight loss
- ejection fraction
- glycemic control
- pulmonary hypertension
- atrial fibrillation
- skeletal muscle
- acute coronary syndrome
- body mass index
- physical activity
- coronary artery disease
- percutaneous coronary intervention