Serine protease inhibitor, SerpinA3n, regulates cardiac remodelling after myocardial infarction.
Qihao SunWei ChenRimao WuBo TaoPing WangBaiming SunJuan F AlvarezFeiyang MaDavid Ceja GalindoSean P MaroneyAnthony J SaviolaKirk C HansenShen LiArjun DebPublished in: Cardiovascular research (2024)
Our study demonstrates a hitherto unappreciated causal role of Serpins in regulating matrix function and post-infarct cardiac remodelling.