Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes.

Megumi OshimaTadashi ToyamaMasakazu HanedaKengo FuruichiTetsuya BabazonoHiroki YokoyamaKunitoshi IsekiShinichi ArakiToshiharu NinomiyaShigeko HaraYoshiki SuzukiMasayuki IwanoEiji KusanoTatsumi MoriyaHiroaki SatohHiroyuki NakamuraMiho ShimizuAkinori HaraHirofumi MakinoTakashi Wadanull null

Published in: PloS one (2018)

Declines in eGFR were strongly associated with subsequent risk of ESRD in Japanese type 2 diabetic patients. In addition to 30% and 40% declines, a 20% decline in eGFR over 2 years could be considered as a candidate surrogate endpoint of ESRD in diabetic kidney disease.

Keyphrases

end stage renal disease
chronic kidney disease
type diabetes
peritoneal dialysis
small cell lung cancer
epidermal growth factor receptor
tyrosine kinase
glycemic control
cardiovascular disease
insulin resistance
wound healing
skeletal muscle
metabolic syndrome