Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure.

Aiguo RenAiguo RenLinlin WangLei JinShanshan LinZhiwen LiJasmine A McDonald

Published in: Clinical epigenetics (2019)

Hypomethylation of Casp8 promoter is associated with the formation of NTDs, and Casp8 hypomethylation may be induced by oxidative stress that resulted from exposure to PAHs.

Keyphrases

oxidative stress
dna methylation
gene expression
transcription factor
polycyclic aromatic hydrocarbons
ischemia reperfusion injury
amino acid
induced apoptosis
health risk assessment
heat shock