Diagnosis, prevalence, and screening of familial dilated cardiomyopathy.
Mary SweetMatthew R G TaylorLuisa MestroniPublished in: Expert opinion on orphan drugs (2015)
As an inherited disease, future FCD studies will focus on elucidating the remaining 60-70% of genetic causes in inherited cases and the pathogenic mechanisms leading to the phenotype. Specifically, a focus on regulatory regions, copy number variation, genetic and environmental modifiers and functional confirmatory investigations will be essential.