Bioinformatic Analysis of Neuroimmune Mechanism of Neuropathic Pain.

Hao YuYang LiuChao LiJianhao WangBo YuQiang WuZiqian XiangShi-Qing Feng

Published in: BioMed research international (2020)

The present study helps us better understand the neuroimmune mechanism of neuropathic pain and provides some novel insights on NP treatment, such as modulation of microglia polarization and targeting bone resorption. Besides, CD68, CTSS, LAPTM5, FCGR3A, and CD53 may be used as early diagnostic biomarkers and the gene HCK can be a therapeutic target.

Keyphrases

neuropathic pain
spinal cord
spinal cord injury
bone loss
bone mineral density
genome wide
copy number
cancer therapy
combination therapy
postmenopausal women
genome wide identification