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Magnesium-Based Temporary Implants: Potential, Current Status, Applications, and Challenges.

Sankaranarayanan SeetharamanDhivya SankaranarayananManoj Gupta
Published in: Journal of functional biomaterials (2023)
Biomedical implants are important devices used for the repair or replacement of damaged or diseased tissues or organs. The success of implantation depends on various factors, such as mechanical properties, biocompatibility, and biodegradability of the materials used. Recently, magnesium (Mg)-based materials have emerged as a promising class of temporary implants due to their remarkable properties, such as strength, biocompatibility, biodegradability, and bioactivity. This review article aims to provide a comprehensive overview of current research works summarizing the above-mentioned properties of Mg-based materials for use as temporary implants. The key findings from in-vitro, in-vivo, and clinical trials are also discussed. Further, the potential applications of Mg-based implants and the applicable fabrication methods are also reviewed.
Keyphrases
  • soft tissue
  • clinical trial
  • current status
  • gene expression
  • tissue engineering
  • risk assessment