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Cigarette smoking is associated with adverse pathological response and increased disease recurrence amongst patients with muscle-invasive bladder cancer treated with cisplatin-based neoadjuvant chemotherapy and radical cystectomy: a single-centre experience.

Luca BoeriMatteo SoligoIgor FrankStephen A BoorjianRobert H ThompsonMatthew TollefsonFernando J QuevedoJohn C ChevilleRobert Jeffrey Karnes
Published in: BJU international (2019)
Cigarette smoking was significantly associated with adverse pathological response to cisplatin-based NAC in patients with MIBC treated with RC. Current smokers were at significantly higher risk of disease recurrence as compared to former and never smokers.
Keyphrases
  • neoadjuvant chemotherapy
  • muscle invasive bladder cancer
  • smoking cessation
  • locally advanced
  • lymph node
  • sentinel lymph node
  • transcription factor
  • free survival
  • early stage