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CA 19-9 but Not IGF-1/IGFBP-2 Is a Useful Biomarker for Pancreatic Ductal Adenocarcinoma (PDAC) and Chronic Pancreatitis (CP) Differentiation.

Barbara WlodarczykLukasz DurkoPrzemysław WłodarczykRenata Talar-WojnarowskaEwa Małecka-Panas
Published in: Journal of clinical medicine (2023)
The presented results indicate that CA 19-9 is a marker demonstrating high potential for PDAC and CP differentiation. The inclusion of additional variables into the model, such as the serum level of IGF-1 or IGFBP-2, slightly increased the sensitivity in differentiating CP from PDAC. The IGF-1/IGFBP-2 ratio turned out to be a good marker of pancreatic diseases, but insufficient for the purpose of CP and PDAC differentiation.
Keyphrases
  • binding protein
  • pi k akt
  • growth hormone
  • signaling pathway
  • cell proliferation
  • magnetic resonance
  • risk assessment
  • climate change
  • human health