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Multiple indicators of gut dysbiosis predict all-cause and cause-specific mortality in solid organ transplant recipients.

J Casper SwarteShuyan ZhangLianne M NieuwenhuisRanko GacesaTim J Knobbenull nullVincent E De MeijerKevin DammanErik A M VerschuurenTji C GanJingyuan FuAlexandra ZhernakovaHermie J M HarmsenHans BlokzijlStephan J L BakkerJohannes R BjörkRinse K Weersmanull null
Published in: Gut (2024)
Gut dysbiosis is consistently associated with mortality in SOTR. Our results support the observations that gut dysbiosis is associated with long-term survival. Since our data do not allow us to infer causality, more preclinical research is needed to understand mechanisms before we can determine whether gut microbiome-directed therapies may be designed to improve long-term outcomes.
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