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Methotrexate plus reduced or full-dose glucocorticoids for the treatment of active, moderate-to-severe Graves' orbitopathy.

Liyun ShenLei YeWei ZhuQin JiaoYulin ZhouShu WangWeiqing WangGuang Ning
Published in: European thyroid journal (2022)
Our study shows that reduced MP plus MTX therapy is effective and safer in treating active and moderate-to-severe GO patients than 4.5 g MP monotherapy.
Keyphrases
  • patient reported
  • early onset
  • high intensity
  • combination therapy
  • end stage renal disease
  • high dose
  • chronic kidney disease
  • newly diagnosed
  • ejection fraction
  • stem cells
  • prognostic factors
  • study protocol