Optimized Anti-Prostate-Specific Membrane Antigen Single-Chain Variable Fragment-Loaded Nanobubbles as a Novel Targeted Ultrasound Contrast Agent for the Diagnosis of Prostate Cancer.

Yu DingQifeng CaoSubo QianXiaolong ChenYuhong XuJian ChenHaibo Shen

Published in: Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine (2019)

These novel PSMA scFv-loaded NBs have proven to be an excellent US contrast agent for imaging PSMA-expressing PCa and have the potential to not only enable efficient and safe molecular imaging but also to serve as a delivery system for targeted PCa therapies.

Keyphrases

prostate cancer
cancer therapy
pet ct
drug delivery
magnetic resonance
pet imaging
radical prostatectomy
high resolution
magnetic resonance imaging
contrast enhanced
wound healing
human health
benign prostatic hyperplasia
mass spectrometry
contrast enhanced ultrasound
risk assessment