Maternal overweight is not an independent risk factor for increased birth weight, leptin and insulin in newborns of gestational diabetic women: observations from the prospective 'EaCH' cohort study.
Raffael OttJens H StupinAndrea LouiElisabeth EilersKerstin MelchiorRebecca C RancourtKaren SchellongThomas ZiskaJoachim W DudenhausenWolfgang HenrichAndreas PlagemannPublished in: BMC pregnancy and childbirth (2018)
Neither overweight/obesity nor gestational weight gain appear to be independent determinants of increased birth weight, insulin and leptin. Rather, 3rd trimester glycemia seems to be crucial for respective neonatal outcomes. Thus, gestational care and future research studies should greatly consider late pregnancy glucose in overweight/obese women with or without GDM, for evaluation of critical causes and interventional strategies against 'perinatal programming of diabesity' in the offspring.
Keyphrases
- weight gain
- birth weight
- type diabetes
- weight loss
- body mass index
- pregnancy outcomes
- glycemic control
- pregnant women
- gestational age
- preterm birth
- bariatric surgery
- healthcare
- metabolic syndrome
- palliative care
- adipose tissue
- high fat diet
- blood glucose
- insulin resistance
- quality improvement
- wound healing
- low birth weight
- blood pressure
- pain management
- health insurance
- case control
- obese patients