Independent effects of 15 commonly prescribed drugs on all-cause mortality among US elderly patients with type 2 diabetes mellitus.
Seo Hyon BaikClement J McDonaldPublished in: BMJ open diabetes research & care (2021)
Among older patients with diabetes, mortality risk decreased importantly with three new diabetes drugs, 3 blood pressure drugs and statins. It increased moderately with sulfonylurea and insulin. Studies of aggressive use of new T2DM drugs instead of sulfonylureas and insulin are needed. Our statin results empirically validate two national guidelines for using statins in older patients with diabetes. However, 23% of study patients never took a statin, suggesting missed opportunities for prevention.
Keyphrases
- cardiovascular disease
- type diabetes
- glycemic control
- blood pressure
- end stage renal disease
- ejection fraction
- newly diagnosed
- coronary artery disease
- chronic kidney disease
- drug induced
- physical activity
- prognostic factors
- peritoneal dialysis
- heart rate
- blood glucose
- hypertensive patients
- insulin resistance
- middle aged
- adipose tissue
- low density lipoprotein
- quality improvement
- skeletal muscle
- case control