Urinary metabolites associate with the presence of diabetic kidney disease in type 2 diabetes and mediate the effect of inflammation on kidney complication.

Caifeng ShiYemeng WanAiqin HeXiaomei WuXinjia ShenXueting ZhuJunwei YangYang Zhou

Published in: Acta diabetologica (2023)

In T2D, several associated urinary metabolites were identified to improve the prediction of DKD. Whether interventions aimed at reducing CMI also reduce the risk of DKD especially in patients with high IL-18 needs further investigations.

Keyphrases

type diabetes
ms ms
oxidative stress
glycemic control
physical activity
cardiovascular disease
insulin resistance
metabolic syndrome
weight loss
skeletal muscle