Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia.
Alik FarberMatthew T MenardMichael S ConteJohn A KaufmanRichard J PowellNiteesh K ChoudhryTaye H HamzaSusan F AssmannMark A CreagerMark J CzirakyMichael D DakeMichael R JaffDiane ReidFlora S SiamiGeorge SopkoChristopher J WhiteMax van OverMichael B StrongMaria F VillarrealMichelle McKeanEzana AzeneAmir AzarbalAndrew BarlebenDavid K ChewLeonardo C ClavijoYvan DouvilleLaura FindeissNitin GargWarren J GasperKristina A GilesPhilip P GoodneyBeau M HawkinsChristine R HermanJeffrey A KalishMatthew C KoopmannIgor A LaskowskiCarlos I Mena-HurtadoRaghu MotaganahalliVincent L RoweAndres SchanzerPeter A SchneiderJeffrey J SiracuseMaarit VenermoKenneth Rosenfieldnull nullPublished in: The New England journal of medicine (2022)
Among patients with CLTI who had an adequate great saphenous vein for surgical revascularization (cohort 1), the incidence of a major adverse limb event or death was significantly lower in the surgical group than in the endovascular group. Among the patients who lacked an adequate saphenous vein conduit (cohort 2), the outcomes in the two groups were similar. (Funded by the National Heart, Lung, and Blood Institute; BEST-CLI ClinicalTrials.gov number, NCT02060630.).
Keyphrases
- coronary artery bypass
- percutaneous coronary intervention
- minimally invasive
- heart failure
- risk factors
- coronary artery bypass grafting
- aortic dissection
- quality improvement
- atrial fibrillation
- type diabetes
- acute coronary syndrome
- coronary artery disease
- metabolic syndrome
- skeletal muscle
- insulin resistance
- adverse drug