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[Gene Therapy for Epilepsy: Clinical Studies are on the Road].

Peter MüllerHolger Lerche
Published in: Fortschritte der Neurologie-Psychiatrie (2023)
For more than 10 years, research has been conducted on gene therapies for the most severe forms of epilepsy, which until now have proven resistant to treatment. First gene therapies are now in clinical trials for pharmacoresistant focal epilepsies and Dravet syndrome. In this article, we describe how these and many more gene therapies work and what they target.
Keyphrases
  • gene therapy
  • clinical trial
  • copy number
  • genome wide
  • genome wide identification
  • dna methylation
  • case report
  • transcription factor
  • drug induced