Photoredox Catalyzed Thioformylation of Terminal Alkynes Using Nitromethane as a Formyl Source.

A photoredox thioformylation of terminal alkynes using nitromethane as a formyl anion equivalent, thereby leading to the synthesis of ( E )-1,2-difunctionalized acrylaldehyde, has been described. The current strategy introduces an adaptable aldehyde function across an alkyne and offers a new route to synthesizing α-alkyl/aryl aldehydes.