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Effects on the Post-translational Modification of H3K4Me3, H3K9ac, H3K9Me2, H3K27Me3, and H3K36Me2 Levels in Cerebral Cortex, Hypothalamus and Pons of Rats after a Systemic Administration of Cannabidiol: A Preliminary Study.

José Carlos Pastrana-TrejoFátima Duarte-AkéRosa Us-CamasClelia De-la-PeñaLinda ParkerRoger G PertweeEric Murillo-Rodríguez
Published in: Central nervous system agents in medicinal chemistry (2021)
The study showed that CBD induced differential effects in levels of PTM on the histones H3K4Me3, H3K9ac, H3K9Me2, H3K27Me3, and H3K36Me2 in several brain regions.
Keyphrases
  • functional connectivity
  • resting state
  • white matter
  • subarachnoid hemorrhage
  • diabetic rats
  • cerebral ischemia
  • drug induced
  • brain injury
  • oxidative stress