Functional Connectivity of the Cerebellar Vermis in Bipolar Disorder and Associations with Mood.

Arshaq SaleemGail HarmataShivangi JainMichelle W VossJess G FiedorowiczAislinn WilliamsJoseph J ShafferJenny Gringer RichardsErcole John BarsottiLeela SathyaputriSamantha L SchmitzGary E ChristensenJeffrey D LongJia XuJohn A WemmieVincent A Magnotta

Published in: bioRxiv : the preprint server for biology (2023)

Together the findings suggest cerebellum may play a compensatory role in bipolar disorder and when it can no longer fulfill this role, depression and mania develop. The proximity of the cerebellar vermis to the skull may make this region a potential target for treatment with transcranial magnetic stimulation.

Keyphrases

bipolar disorder
functional connectivity
transcranial magnetic stimulation
major depressive disorder
resting state
high frequency
depressive symptoms
risk assessment
sleep quality
physical activity
combination therapy
climate change
replacement therapy