Hyperprolactinemia is associated with a high prevalence of serum autoantibodies, high levels of inflammatory cytokines and an abnormal distribution of peripheral B-cell subsets.
Yaoyang LiuZhiguo ZhangQianmei JinYang LiuZijian KangYongbao HuoZhengwen HeXu FengJian YinXin WuHuaizhou WangHuji XuPublished in: Endocrine (2019)
Women with HPRL had a higher prevalence of autoantibodies, higher serum levels of IL-4 and IL-6, and more BND cells, antibody-secreting B cells and unswitched memory B cells than healthy women. These data imply that a high level of PRL is associated with autoimmune diseases.
Keyphrases
- systemic lupus erythematosus
- induced apoptosis
- cell cycle arrest
- polycystic ovary syndrome
- risk factors
- working memory
- electronic health record
- endoplasmic reticulum stress
- oxidative stress
- metabolic syndrome
- cell death
- adipose tissue
- skeletal muscle
- breast cancer risk
- deep learning
- cell proliferation
- artificial intelligence