Effect of altitude and acetazolamide on sleep and nocturnal breathing in healthy lowlanders 40y of age or older. Data from a randomized trial.

Laura C GrafMichael FurianKonstantinos BitosMaamed MademilovAinura AbdraevaJana BuenzliSimone BuenzliShaira AidaralievaUlan SheralievLaura C MayerSimon R SchneiderTalant M SooronbaevStéphanie SaxerKonrad E Bloch

Published in: Sleep (2022)

During a night at 3100m, healthy lowlanders aged 40y or older revealed hypoxemia, sleep apnea and disturbed sleep. Preventive acetazolamide treatment improved oxygenation and nocturnal breathing but had no effect on sleep duration and structure.

Keyphrases

sleep apnea
sleep quality
physical activity
obstructive sleep apnea
positive airway pressure
community dwelling
middle aged
depressive symptoms
blood pressure
electronic health record
big data
single cell
blood flow
replacement therapy
data analysis