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Prevalence, Characteristics and Outcomes of Older Patients with Hereditary versus Wild-Type Transthyretin Amyloid Cardiomyopathy.

Aldostefano PorcariYousuf RazviAmbra MasiRishi PatelAdam IoannouMuhammad U RaufDavid F HuttDorota RowczenioJanet GilbertsonAna Martinez-NaharroLucia VenneriCarol WhelanHelen LachmannAshutosh WechalekarCandida Cristina QuartaMarco MerloGianfranco SinagraPhilip N HawkinsMarianna FontanaJulian D Gillmore
Published in: European journal of heart failure (2023)
Up to 20.7% of elderly patients with ATTR-CM have a pathogenic TTR variant. These findings support routine sequencing of the TTR gene in all patients with ATTR-CM regardless of age. This article is protected by copyright. All rights reserved.
Keyphrases
  • wild type
  • risk factors
  • heart failure
  • single cell
  • copy number
  • clinical practice
  • genome wide
  • type diabetes
  • dna methylation
  • adipose tissue
  • atrial fibrillation