Immunomodulation and Reduction of Thromboembolic Risk in Hospitalized COVID-19 Patients: Systematic Review and Meta-Analysis of Randomized Trials.

Dimitrios SagrisMatilda FlorentinPanagiotis T TasoudisEleni KorompokiNikolaos GatselisEvangelos J Giamarellos-BourboulisHaralampos MilionisJames DouketisAlex C SpyropoulosGeorge DalekosGeorge Ntaios

Published in: Journal of clinical medicine (2021)

We did not identify a statistically significant effect of immunomodulation on prevention of thromboembolic events in COVID-19. However, given the large effect estimate for VTE prevention, especially in the patients treated with IL-6 antagonists, we cannot exclude a potential effect of immunomodulation.

Keyphrases

systematic review
sars cov
coronavirus disease
venous thromboembolism
meta analyses
atrial fibrillation
respiratory syndrome coronavirus
human health